Publications

Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies
Guest User Guest User

Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies

Carmen Martin-Alonso, Shervin Tabrizi , Kan Xiong, Timothy Blewett, Sainetra Sridhar, Andjela Crnjac, Sahil Patel, Zhenyi An, Ahmet Bekdemir, Douglas Shea, Shih-Ting Wang, Sergio Rodriguez-Aponte, Christopher A. Naranjo, Justin Rhoades, Jesse D. Kirkpatrick, Heather E. Fleming, Ava P. Amini, Todd R. Golub, J. Christopher Love , Sangeeta N. Bhatia, and Viktor A. Adalsteinsson.

Science (2024)

Manuscript (PDF)

Cited by:

Tina Moser, Ellen Heitzer, Surpassing sensitivity limits in liquid biopsy. Science383,260-261 (2024). (PDF).

Sarah Crunkhorn, Improving liquid biopsy for cancer detection. Nature Reviews Drug Discovery (2024). (PDF).

News coverage:

MIT News Feature (here), Broad Press Release (here).

Read More
Inhalable point-of-care urinary diagnostic platform
Guest User Guest User

Inhalable point-of-care urinary diagnostic platform

Qian Zhong, Edward K. W. Tan, Carmen Martin-Alonso, Tiziana Parisi, Liangliang Hao, Jesse D. Kirkpatrick, Tarek Fadel, Heather E. Fleming, Tyler Jacks, Sangeeta N. Bhatia.

Science Advances (2024)

Manuscript (PDF)

News coverage: MIT News Feature (here), HHMI Feature (here).

Read More
Low protease activity in B cell follicles promotes retention of intact antigens after immunization
Guest User Guest User

Low protease activity in B cell follicles promotes retention of intact antigens after immunization

Aereas Aung, Ang Cui, Laura Maiorino, Ava P. Amini, Justin R. Gregory, Maurice Bukenya, Yiming Zhang, Heya Lee, Christopher A. Cottrell, Duncan M. Morgan, Murillo Silva, Heikyung Suh, Jesse D. Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M. Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, J. Christopher Love, Phillip Huyett, Douglas S. Kwon, Nir Hacohen, William R. Schief, Sangeeta N. Bhatia, Darrell J. Irvine

Science (2023)

Manuscript (PDF)

Read More
Cancer nanomedicine
Guest User Guest User

Cancer nanomedicine

Sangeeta N. Bhatia , Xiaoyuan Chen , Marina A. Dobrovolskaia and Twan Lammers

Nature Cancer Reviews (2022)

Manuscript (PDF)

Read More
Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes
Guest User Guest User

Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes

Whitney A. Scoon, Liliana Mancio-Silva, Ellen L. Suder, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, John G. Bernbaum, Steve Mazur, Reed F. Johnson, Judith Olejnik, Elizabeth Y. Flores, Aditya Mithal, Feiya Wang, Adam J. Hume, Joseph E. Kaserman, Sandra March-Riera, Andrew A. Wilson, Sangeeta N. Bhatia, Elke Mühlberger, Gustavo Mostoslavsky

Cell Reports (2022)

Manuscript (PDF)

Read More
Direct capture of neutralized RBD enables rapid point-of-care assessment of SARS-CoV-2 neutralizing antibody titer
Guest User Guest User

Direct capture of neutralized RBD enables rapid point-of-care assessment of SARS-CoV-2 neutralizing antibody titer

Guinevere G. Connelly, Orville O. Kirkland, Seven Bohannon, Daniel C. Lim, Robert M. Wilson, Edward J. Richards, Dousabel M. Tay, Hyuk Jee, Riley D. Hellinger, Ngoc K. Hoang, Liang Hao, Arnav Chhabra, Carmen Martin-Alonso, Edward K.W. Tan, Angela N. Koehler, Michael B. Yaffe, Wendy B. London, Pui Y. Lee, Florian Krammer, Robert C. Bohannon, Sangeeta N. Bhatia, Hadley D. Sikes, Hojun Li
Cell Reports Methods(2022)

Manuscript (PDF)

Read More
A single-cell liver atlas of Plasmodium vivax infection
Guest User Guest User

A single-cell liver atlas of Plasmodium vivax infection

Liliana Mancio-Silva, Nil Gural, Eliana Real, Marc H. Wadsworth II, Vincent L. Butty, Sandra March, Niketa Nerurkar, Travis K. Hughes, Wanlapa Roobsoong, Heather E. Fleming, Charlie A. Whittaker, Stuart S. Levine, Jetsumon Sattabongkot, Alex K. Shalek, and Sangeeta N. Bhatia
Cell Host & Microbe (2022)

Manuscript (PDF)

Read More
Early detection of cancer
Guest User Guest User

Early detection of cancer

David Crosby, Sangeeta Bhatia, Kevin M. Brindle, Lisa M. Coussens, Caroline Dive, Mark Emberton, Sadik Esener, Rebecca C. Fitzgerald, Sanjiv S. Gambhir†, Peter Kuhn, Timothy R. Rebbeck, Shankar Balasubramanian
Science (2022)

Manuscript (PDF)

Read More
Distinct Hepatic Gene-Expression Patterns of NAFLD in Patients With Obesity
Guest User Guest User

Distinct Hepatic Gene-Expression Patterns of NAFLD in Patients With Obesity

Sonu Subudhi, Hannah K. Drescher, Laura E. Dichtel, Lea M. Bartsch, Raymond T. Chung, Matthew M. Hutter, Denise W. Gee, Ozanan R. Meireles, Elan R. Witkowski, Louis Gelrud, Ricard Masia, Stephanie A. Osganian, Jenna L. Gustafson, Steve Rwema, Miriam A. Bredella, Sangeeta N. Bhatia, Andrew Warren, Karen K. Miller, Georg M. Lauer, Kathleen E. Corey
Hepatology Communications (2022)

Manuscript (PDF)

Read More