Publications
Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors
S. C. Cazanave, A. D. Warren , M. Pacula , F. Touti , A. Zagorska, N. Gural, E. K. Huang , S. Sherman, M. Cheema , S. Ibarra , J. Bates, A. N. Billin, J. T. Liles, G. R. Budas, D. G. Breckenridge , D. Tiniakos, V. Ratziu, A. K. Daly, O. Govaere , Q. M. Anstee, L. Gelrud, J. Luther, R. T. Chung, K. E. Corey , W. Winckler, S. Bhatia, G A. Kwong
Science Translational Medicine (2021)
Manuscript (PDF)
Protease activity sensors enable real-time treatment response monitoring in lymphangioleiomyomatosis
J. D. Kirkpatrick, A. P. Soleimany, J. S. Dudani, H-J Liu, H. C. Lam, C. Priolo, E. P. Henske, S. N. Bhatia
European Respiratory Journal (2021)
Manuscript (PDF)
Synthetic biomarkers: a twenty-first century path to early cancer detection
G. A. Kwong, S. Ghosh, L. Gamboa, C. Patriotis, S. Srivastava and S. N. Bhatia
Nature Reviews Cancer (2021)
Manuscript (PDF)
Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function
A.G. Schepers, J. Shan, A. G. Cox, A. Huang, H. Evans, C. Walesky, H. E. Fleming, W. Goessling, and S. N. Bhatia
ACS Chemical Biology (2021)
Manuscript (PDF)
Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection
J. He, L. Nissim, A. P. Soleimany, A. Binder-Nissim, H. E. Fleming, T. K. Lu, S. N. Bhatia
ACS Synthetic Biology (2021)
Manuscript (PDF)
Evidential Deep Learning for Guided Molecular Property Prediction and Discovery
A.P. Soleimany, A. Amini, S. Goldman, D. Rus, S.N. Bhatia, and C.W. Coley
ACS Central Science (2021)
Manuscript (PDF)
Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity
A. Mwakingwe-Omari, S. A. Healy, J. Lane, D. M. Cook, S. Kalhori, C. Wyatt, A. Kolluri, O. Marte-Salcedo, A. Imeru, M. Nason, L. K. Ding, H. Decederfelt, J. Duan, J. Neal, J. Raiten, G. Lee, J. C. C. Hume, J. E. Jeon, I. Ikpeama, N. Kc, S. Chakravarty, T. Murshedkar, L. W. P. Church, A. Manoj, A. Gunasekera, C. Anderson, S. C. Murphy, S. March, S. N. Bhatia, E. R. James, P. F. Billingsley, B. K. L. Sim, T. L. Richie, I. Zaidi, S. L. Hoffman, P. E. Duffy
Nature (2021)
Manuscript (PDF), Nature News and Views feature (Link), Nature News feature (Link)
Opening the path to biotech
S.N. Bhatia, N. Hopkins, S. Hockfield
Science (2021)
Manuscript (PDF)
In Vivo Gene Expression Dynamics of Tumor-Targeted Bacteria
T. Danino, J. Lo, A. Prindle, J. Hasty, S. N. Bhatia,
ACS Synthetic Biology (2012)
Manuscript + Supporting information (PDF)
Genetic Circuits in Salmonella typhimurium
A. Prindle, J. Selimkhanov, T. Danino, P. Samayoa, A. Goldberg, S. N. Bhatia, J. Hasty
ACS Synthetic Biology (2012)
Manuscript + Supporting information (PDF)
Bioengineering Methods for Analysis of Cells In Vitro
G. H. Underhill, P. Galie, C.S. Chen, S. N. Bhatia
Annu. Rev. Cell Dev. Biol. (2012)
Manuscript (PDF)
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis
N. E. Reticker-Flynn, D. F. B. Malta, M. M. Winslow, J. M. Lamar, M. J. Xu, G. H. Underhill, R. O. Hynes, T. E. Jacks, S. N. Bhatia
Nature Communications (2012)
Manuscript + Supporting information (PDF)
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy
C. P. El-Haibi, G. W. Bell, J. Zhang, A. Y. Collmann, D. Wood, C. M. Scherber, E. Csizmadia, O. Mariani, C. Zhu, A. Campagne, M. Toner, S. N. Bhatia, D. Irimia, A. Vincent-Salomon, A. E. Karnoub
PNAS (2012)
Manuscript + Supporting information (PDF)
Cancer Vulnerabilities Unveiled by Genomic Loss
D. Nijhawan, T. I. Zack, Y. Ren, M. R. Strickland, R. Lamothe, S. E. Schumacher, A. Tsherniak, H. C. Besche, J. Rosenbluh, S. Shehata, G. S. Cowley, B. A. Weir, A. L. Goldberg, J. P. Mesirov, D. E. Root, S. N. Bhatia, R. Beroukhim, W. C. Hahn
Cell (2012)
Manuscript + Supporting information (PDF)
The challenges posed by cancer heterogeneity
S.N. Bhatia, J.V. Frangioni, R. M. Hoffman, A. J. Iafrate, K. Polyak
Nature Biotechnology (2012)
Manuscript (PDF)
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
J. S. Miller, K. R. Stevens, M. T. Yang, B. M. Baker, D.-H. T. Nguyen, D. M. Cohen, E. Toro, A. A. Chen, P. A. Galie, X. Yu, R. Chaturvedi, S. N. Bhatia, C. S. Chen
Nature Materials (2012)
Manuscript (PDF)
A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease
D. K. Wood, A. Soriano, L. Mahadevan, J. M. Higgins S. N. Bhatia
Science Translational Medicine (2012)
Manuscript (PDF)
Modeling hepatitis C virus infection using human induced pluripotent stem cells
R. E. Schwartz, K. Trehan, L. Andrus, T. P. Sheahan, A. Ploss, S. A. Duncan, C. M. Rice, S. N. Bhatia
PNAS (2012)
Manuscript (PDF)
What is the greatest regulatory challenge in the translation of biomaterials to the clinic?
G. D. Prestwich, S. Bhatia, C. K. Breuer, S. L. M. Dahl, C. Mason, R. McFarland, D. J. McQuillan, J. Sackner-Bernstein, J. Schox, W. E. Tente, A. Trounson
Science Translational Medicine (2012)
Manuscript (PDF)