Publications
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
A. Ploss, S. R. Khetani, C. T. Jones, A. J. Syder, K. Trehan, V. A. Gaysinskaya, K. Mu, K. Ritola, C. M. Rice, and S. N. Bhatia
Proceedings of the National Academy of Sciences (2010)
Manuscript (PDF), Supporting information (PDF)
Peptide Spiders: Peptide–Polymer Conjugates to Traffic Nucleic Acids
E. J. Kwon, H. Ko, S.N. Bhatia
Mol. Pharm. (2020)
Manuscript (PDF)
Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination
Suscovich, T. J., Fallon, J. K., Das, J., Demas, A. R., Crain, J., Linde, C. H., Michell, A., Natarajan, H., Arevalo, C., Broge, T., Linnekin, T., Kulkarni, V., Lu, R., Slein, M. D., Luedemann, C., Marquette, M., March, S., Weiner, J., Gregory, S., Coccia, M., Flores-Garcia, Y., Zavala, F., Ackerman, M. E., Bergmann-Leitner, E., Hendriks, J., Sadoff, J., Dutta, S., Bhatia, S. N., Lauffenburger, D. A., Jongert, E., Wille-Reece, U. & Alter, G.
Sci. Transl. Med. 12, (2020)
Manuscript (PDF)
Controlled apoptosis of stromal cells to engineer human microlivers
A.X. Chen, A. Chhabra, H.-H. G.Song, H.E. Fleming, C.S. Chen, and S.N. Bhatia
Advanced Functional Materials (2020)
Manuscript (PDF)
Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics
C. G. Buss and S. N. Bhatia
Proceedings of the National Academy of Sciences (2020)
Manuscript (PDF)
Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines
N. K. Mehta, Pradhan, R. V., Soleimany, A. P., Moynihan, K. D., Rothschilds, A. M., Momin, N., Rakhra, K., Mata-Fink, J., Bhatia, S. N., K. Wittrup, D., and Irvine, D. J.
Nature Biomedical Engineering. (2020)
Manuscript (PDF)
Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma
C. Tian, hlund, D. Ö., Rickelt, S., m, Tö, Huang, Y., Hao, L., Zhao, R. T., Franklin, O., Bhatia, S. N., Tuveson, D. A., and Hynes, R. O.
Cancer Research (2020)
Manuscript (PDF)
Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers
S. Ng, March, S., Galstian, A., Gural, N., Stevens, K. R., Mota, M. M., and Bhatia, S. N.
Scientific Reports (2017)
Manuscript (PDF)
Ultrasensitive tumour-penetrating nanosensors of protease activity
E. J. Kwon†, Dudani, J. S. †, and Bhatia, S. N.
Nature Biomedical Engineering (2017)
Manuscript (PDF)
Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections
E. J. Kwon, Skalak, M., Bertucci, A., Braun, G., Ricci, F., Ruoslahti, E., Sailor, M. J., and Bhatia, S. N.
Advanced Materials, vol. 29, no. 35, pp. 1-9, 2017.
Manuscript (PDF), Supporting information (PDF)
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
K. R. Stevens, M.A. Scull, V. Ramanan, C.L. Fortin, R.R. Chaturvedi, K.A. Knouse, J.W. Xiao, C. Fung, T. Mirabella, A.X. Chen, M.G. McCue, M.T. Yang, H.E. Fleming, K. Chung, Y.P. de Jong, C.S. Chen, C.M. Rice, and S.N. Bhatia.
Science Translational Medicine (2017)
Manuscript (PDF)
Depolarization signatures map gold nanorods within biological tissue
N. Lippok, Villiger, M., Albanese, A., Meijer, E. F. J., Chung, K., Padera, T. P., Bhatia, S. N., and Bouma, B. E.
Nature Photonics (2017)
Manuscript (PDF)
Future cancer research priorities in the USA: a Lancet Oncology Commission
E. M. Jaffee, Van Dang, C., Agus, D. B., Alexander, B. M., Anderson, K. C., Ashworth, A., Barker, A. D., Bastani, R., Bhatia, S., Bluestone, J. A., Brawley, O., Butte, A. J., Coit, D. G., Davidson, N. E., Davis, M., DePinho, R. A., Diasio, R. B., Draetta, G., A Frazier, L., Futreal, A., Gambhir, S. S., Ganz, P. A., Garraway, L., Gerson, S., Gupta, S., Heath, J., Hoffman, R. I., Hudis, C., Hughes-Halbert, C., Ibrahim, R., Jadvar, H., Kavanagh, B., Kittles, R., Le, Q. - T., Lippman, S. M., Mankoff, D., Mardis, E. R., Mayer, D. K., McMasters, K., Meropol, N. J., Mitchell, B., Naredi, P., Ornish, D., Pawlik, T. M., Peppercorn, J., Pomper, M. G., Raghavan, D., Ritchie, C., Schwarz, S. W., Sullivan, R., Wahl, R., Wolchok, J. D., Wong, S. L., and Yung, A.
The Lancet Oncology (2017)
Manuscript (PDF)
Activity-Based Diagnostics: An emerging paradigm for disease detection and monitoring
A.P. Soleimany and S.N. Bhatia
Trends in Molecular Medicine (2020)
Manuscript (PDF)
Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling
J. D. Kirkpatrick, A. D. Warren, A. P. Soleimany, P. M. K. Westcott, J. C. Voog, C. Martin-Alonso, H. E. Fleming, T. Tammela, T. Jacks, and S. N. Bhatia
Science Translational Medicine (2020)
Manuscript (PDF)
Genetic Encoding of Targeted Magnetic Resonance Imaging Contrast Agents for Tumor Imaging
S. Schuerle, M. Furubayashi, A. P. Soleimany, T. Gwisai, W. Huang, C. Voigt, and S. N. Bhatia
ACS Synth. Biol (2020)
Manuscript (PDF)
Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes
E. Michailidis, K. Vercauteren, L. Mancio-Silva, L. Andrus, C. Jahan, I. Ricardo-Lax, C. Zou, M. Kabbani, P. Park, C. Quirk, C. Pyrgaki, B. Razooky, L. Verhoye, I. Zoluthkin, W. Lu, S.J. Forbes, L. Chiriboga, N.D. Theise, R.W. Herzog, H. Suemizu, W.M. Schneider, A. Shlomai, P. Meuleman, S.N. Bhatia, C.M. Rice, Y.P. de Jong.
Proc Natl Acad Sci USA (2020)
Targeting Liver Stage Malaria With Metformin
Vera, I. M., Grilo Ruivo, M. T., Lemos Rocha, L. F., Marques, S., Bhatia, S. N., Mota, M. M. & Mancio-Silva, L.
JCI Insight (2019)
Manuscript (PDF)
Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing
N. Boehnke, S. Correa, L. Hao, W. Wang, J. P. Straehla, S. N. Bhatia, P. T. Hammond.
Angew Chem Int Ed Engl (2020)
Manuscript (PDF)