Publications
Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes
P. K. Jain, J. H. Lo, S. Rananaware, M. Downing, A. Panda, M. Tai, S. Raghavan, H. E. Fleming, S. N. Bhatia.
Nanoscale (2019)
Manuscript (PDF)
Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer
M.-E. Gilles, L. Hao, K. Brown, J. Lim, S. N. Bhatia, F. J. Slack
Oncotarget (2019)
Manuscript (2019)
Renal clearable catalytic gold nanoclusters for in vivo disease monitoring
C. N. Loynachan †, A. P. Soleimany †, J. S. Dudani, Y. Lin, A. Najer, A. Bekdemir, Q. Chen, S. N. Bhatia, and M. M. Stevens
Nat. Nanotechnol (2019)
Manuscript (PDF)
Antimalarial Activity of Primaquine Operates via a Two-Step Biochemical Relay
Camarda, G., Jirawatcharadech, P., Priestley, R. S., Saif, A., March, S., Wong, M. H. L., Leung, S., Miller, A. B., Baker, D. A., Alano, P., Paine, M. J. I., Bhatia, S. N., O’Neill, P. M., Ward, S. A. & Biagini, G. A.
Nat. Commun. (2019)
Manuscript (PDF)
Synthetic and living micropropellers for convection-enhanced nanoparticle transport
Schuerle, S., Soleimany, A. P., Yeh, T., Anand, G. M., Häberli, M., Fleming, H. E., Mirkhani, N., Qiu, F., Hauert, S., Wang, X., Nelson, B. J. & Bhatia, S. N.
Sci. Adv. (2019).
Manuscript (PDF)
Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles
Werling, K., Shaw, W. R., Itoe, M. A., Westervelt, K. A., Marcenac, P., Paton, D. G., Peng, D., Singh, N., Smidler, A. L., South, A., Deik, A. A., Mancio-Silva, L., Demas, A. R., March, S., Calvo, E., Bhatia, S. N., Clish, C. B. & Catteruccia, F.
Cell (2019)
Manuscript (PDF)
Improving drug discovery by nucleic acid delivery in engineered human microlivers
L. Mancio-Silva, H. E. Fleming, A. B. Miller, S. Milstein, A. Liebow, P. Haslett, L. Sepp-Lorenzino, and S. N. Bhatia.
Cell Metabolism (2019)
Manuscript (PDF)
Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes
Rohani, N., Hao, L., Alexis, M. S., Joughin, B. A., Krismer, K., Moufarrej, M. N., Soltis, A. R., Lauffenburger, D. A., Yaffe, M. B., Burge, C. B., Bhatia, S. N. & Gertler, F. B.
Cancer Res (2019)
Manuscript (PDF)
Uncovering and Mitigating Algorithmic Bias through Learned Latent Structure
A. Amini†, Soleimany, A. †, Schwarting, W., Bhatia, S. N., and Rus, D.
AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society, 2019
Manuscript (PDF)
Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes
S. Chaturantabut, Shwartz, A., Evason, K. J., Cox, A. G., Labella, K., Schepers, A. G., Yang, S., Aravena, M., Houvras, iv, Y., Mancio-Silva, L., Romano, S., Gorelick, D. A., Cohen, D. E., Zon, L. I., Bhatia, S. N., North, T. E., and Goessling, W.
Gastroenterology, 2019
Manuscript (PDF)
Protease activity sensors noninvasively classify bacterial infections and antibiotic responses
C. Buss †, J.S. Dudani †, R. Akana, H.E. Fleming, and S.N. Bhatia
EBioMedicine (2018)
Manuscript (PDF)
Harnessing Protease Activity to Improve Cancer Care
J.S. Dudani, A.D. Warren, S.N. Bhatia.
Annu. Rev. Cancer Biol (2018)
Manuscript (PDF)
A Plasmodium berghei sporozoite-based vaccination platform against human malaria
A. M. Mendes, Machado, M., alves-Rosa, Nç, Reuling, I. J., Foquet, L., Marques, áudia, Salman, A. M., Yang, A. S. P., Moser, K. A., Dwivedi, A., Hermsen, C. C., nez-Díaz, éné, Viera, S., Santos, J. M., Albuquerque, ês, Bhatia, S. N., Bial, J., Angulo-Barturen, ñigo, Silva, J. C., Leroux-Roels, G., Janse, C. J., Khan, S. M., Mota, M. M., Sauerwein, R. W., and Prudêncio, M.
npj Vaccines, vol. 3, 2018.
Manuscript (PDF)
iRGD-guided tumor-penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer
J. H. Lo†, Hao, L. †, Muzumdar, M. D., Raghavan, S., Kwon, E. J., Pulver, E. M., Hsu, F., Aguirre, A. J., Wolpin, B. M., Fuchs, C. S., Hahn, W. C., Jacks, T., and Bhatia, S. N.
Molecular Cancer Therapeutics (2018)
Manuscript (PDF)
Classification of prostate cancer using a protease activity nanosensor library
J. S. Dudani, Ibrahim, M., Kirkpatrick, J., Warren, A. D., and Bhatia, S. N.
Proc Natl Acad Sci U S A (2018)
Manuscript (PDF)
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer
S. R. Viswanathan, Nogueira, M. F., Buss, C. G., Krill-Burger, J. M., Wawer, M. J., Malolepsza, E., Berger, A. C., Choi, P. S., Shih, J., Taylor, A. M., Tanenbaum, B., Pedamallu, C. Sekhar, Cherniack, A. D., Tamayo, P., Strathdee, C. A., Lage, K., Carr, S. A., Schenone, M., Bhatia, S. N., Vazquez, F., Tsherniak, A., Hahn, W. C., and Meyerson, M.
Nature Genetics (2018)
Manuscript (PDF)
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite
Kisalu, N.K., Idris, A.H., Weidle, C., Flores-Garcia, Y., Flynn, B.J., Sack, B.K., Murphy, Schön A., Freire, E., Francica, J.R., Miller, A.B., Gregory, J., March, S., Liao, H.X., Haynes, B.F., Wiehe, K., Trama, A.M., Saunders, K.O., Gladden, M.A., Monroe, A., Bonsignori, M., Kanekiyo, M., Wheatley, A.K., McDermott, A.B., Farney, S.K., Chuang, G.Y., Zhang, B., Kc, N., Chakravarty, S., Kwong, P.D., Sinnis, P., Bhatia, S.N., Kappe, S.H.I., Sim, B.K.L., Hoffman, S.L., Zavala, F., Pancera, M., and Seder, R.A.
Nature Medicine (2018)
Manuscript (PDF)
In vitro culture, drug sensitivity, and transcriptome of plasmodium vivax hypnozoites
N. Gural, L. Mancio-Silva, A.B. Miller, A. Galstian, V.L. Butty, S.S. Levine, R. Patrapuvich, S.P. Desai, S.A. Mikolajczak, S.H.I. Kappe, H.E. Fleming, S. March, J. Sattabongkot, and S.N. Bhatia
Cell Host & Microbe (2018)
Manuscript (PDF)
Personalized RNA-medicine for pancreatic cancer
M. - E. Gilles, Hao, L., Huang, L., Rupaimoole, R., Lopez-Casas, P. P., Pulver, E., Jeong, J. Cheol, Muthuswamy, S. K., Hidalgo, M., Bhatia, S. N., and Slack, F. J.
Clinical Cancer Research (2018)
Manuscript (PDF)
Engineered Livers for Infectious Diseases
N. Gural, Mancio-Silva, L., He, J., and Bhatia, S. N.
Cellular and Molecular Gastroenterology and Hepatology (2018)
Manuscript (PDF)