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A robust cell culture system supporting the complete life cycle of hepatitis B virus

E. Michailidis, Pabon, J., Xiang, K., Park, P., Ramanan, V., Hoffmann, H. - H., Schneider, W. M., Bhatia, S. N., de Jong, Y. P., Shlomai, A., and Rice, C. M., “A robust cell culture system supporting the complete life cycle of hepatitis B virus”

Scientific Reports (2017)

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Engineering synthetic breath biomarkers for respiratory disease

L.W. Chan, M.N. Anahtar, T.-H. Ong, K.E. Hern, R.R. Kunz, and S.N. Bhatia
Nature Nanotechnology (2020)

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Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas

Y. Ren, Sagers, J. E., Landegger, L. D., Bhatia, S. N., and Stankovic, K. M., “Tumor-Penetrating Delivery of siRNA against TNFα to Human Vestibular Schwannomas”

Scientific Reports (2017)

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Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

L. T. Geller†, Barzily-Rokni, M. †, Danino, T., Jonas, O. H., Shental, N., Nejman, D., Gavert, N., Zwang, Y., Cooper, Z. A., Shee, K., Thaiss, C. A., Reuben, A., Livny, J., Avraham, R., Frederick, D. T., Ligorio, M., Chatman, K., Johnston, S. E., Mosher, C. M., Brandis, A., Fuks, G., Gurbatri, C., Gopalakrishnan, V., Kim, M., Hurd, M. W., Katz, M., Fleming, J., Maitra, A., Smith, D. A., Skalak, M., Bu, J., Michaud, M., Trauger, S. A., Barshack, I., Golan, T., Sandbank, J., Flaherty, K. T., Mandinova, A., Garrett, W. S., Thayer, S. P., Ferrone, C. R., Huttenhower, C., Bhatia, S. N., Gevers, D., Wargo, J. A., Golub, T. R., and Straussman, R.
Science (2017)

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Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

N. Kato†, Comer, E. †, Sakata-Kato, T., Sharma, A., Sharma, M., Maetani, M., Bastien, J., Brancucci, N. M., Bittker, J. A., Corey, V., Clarke, D., Derbyshire, E. R., Dornan, G., Duffy, S., Eckley, S., Itoe, M. A., Koolen, K. M. J., Lewis, T. A., Lui, P. S., Lukens, A. K., Lund, E., March, S., Meibalan, E., Meier, B. C., McPhail, J., Mitasev, B., Moss, E. L., Sayes, M., VanGessel, Y., Wawer, M. J., Yoshinaga, T., Zeeman, A. - M., Avery, V. M., Bhatia, S. N., Burke, J. E., Catteruccia, F., Clardy, J. C., Clemons, P. A., Dechering, K. J., Duvall, J. R., Foley, M. A., Gusovsky, F., Kocken, C. H. M., Marti, M., Morningstar, M. L., Munoz, B., Neafsey, D. E., Sharma, A., Winzeler, E. A., Wirth, D. F., Scherer, C. A., and Schreiber, S. L.
Nature (2016)

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Host AMPK Is a Modulator of Plasmodium Liver Infection

M. T. Grilo Ruivo, Vera, I. Medina, Sales-Dias, J., Meireles, P., Gural, N., Bhatia, S. N., Mota, M. M. ‡, and Mancio-Silva, L. ‡
Cell Rep. (2016)

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Comparison of Modular PEG Incorporation Strategies for Stabilization of Peptide–siRNA Nanocomplexes

J. H. Lo†, Kwon, E. J. †, Zhang, A. Q., Singhal, P., and Bhatia, S. N.
Bioconjugate Chemistry (2016)

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Magnetically Actuated Protease Sensors for in Vivo Tumor Profiling

S. Schuerle †, Dudani, J. S. †, Christiansen, M. G., Anikeeva, P. ‡, and Bhatia, S. N. ‡
Nano Letters (2016)

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High-Throughput Platform for Identifying Molecular Factors Involved in Phenotypic Stabilization of Primary Human Hepatocytes In Vitro

J. Shan, Logan, D. J., Root, D. E., Carpenter, A. E., and Bhatia, S. N.
Journal of Biomolecular Screening (2016)

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Synchronized cycles of bacterial lysis for in vivo delivery

O. M. Din†, Danino, T. †, Prindle, A., Skalak, M., Selimkhanov, J., Allen, K., Julio, E., Atolia, E., Tsimring, L. S., Bhatia, S. N. ‡, and Hasty, J. ‡,
Nature (2016)

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Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries

E. J. Kwon, Skalak, M., Bu, R. Lo, and Bhatia, S. N.
ACS Nano (2016)

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Self-Sealing Porous Silicon-Calcium Silicate Core–Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain

J. Kang, Joo, J., Kwon, E. J., Skalak, M., Hussain, S., She, Z. - G., Ruoslahti, E., Bhatia, S. N., and Sailor, M. J.
Advanced Materials (2016)

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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

W. C. Van Voorhis, Adams, J. H., Adelfio, R., Ahyong, V., Akabas, M. H., Alano, P., Alday, A., Resto, Yán, Alsibaee, A., Alzualde, A., Andrews, K. T., Avery, S. V., Avery, V. M., Ayong, L., Baker, M., Baker, S., Ben Mamoun, C., Bhatia, S.,… and Willis, P. A.
PLOS Pathogens, vol. 12, no. 7 (2016)

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A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries

A. P. Mann†, Scodeller, P. †, Hussain, S., Joo, J., Kwon, E., Braun, G. B., Mölder, T., She, Z. - G., Kotamraju, V. Ramana, Ranscht, B., Krajewski, S., Teesalu, T., Bhatia, S., Sailor, M. J., and Ruoslahti, E.
Nat Communications (2016)

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Porous silicon–graphene oxide core–shell nanoparticles for targeted delivery of siRNA to the injured brain

J. Joo, Kwon, E. J., Kang, J., Skalak, M., Anglin, E. J., Mann, A. P., Ruoslahti, E., Bhatia, S. N., and Sailor, M. J.
Nanoscale Horiz., vol. 1, no. 5, pp. 407 - 414 (2016)

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Engineering a perfusable 3D human liver platform from iPS cells

A. Schepers, Li, C., Chhabra, A., Seney, B. Tschudy, and Bhatia, S.
Lab Chip, vol. 16, pp. 2644-2653 (2016)

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Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors

P. K. Jain, Ramanan, V., Schepers, A. G., Dalvie, N. S., Panda, A., Fleming, H. E., and Bhatia, S. N.
Angewandte Chemie International Edition, vol. 55, no. 40, pp. 12440–12444 (2016)

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Infection of laboratory colonies of Anopheles mosquitoes with Plasmodium vivax from cryopreserved clinical isolates.

K. Shaw-Saliba, Clarke, D., Santos, J. M., Menezes, M. José, Lim, C., Mascarenhas, A., Chery, L., Gomes, E., March, S., Bhatia, S. N., Rathod, P. K., Ferreira, M. U., Catteruccia, F., and Duraisingh, M. T.
Int J Parasitol, vol. 46, no. 11, pp. 679-683 (2016)

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Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies

V. Ramanan†, Trehan, K. †, Ong, M. - L., Luna, J. M., Hoffmann, H. - H., Espiritu, C., Sheahan, T. P., Chandrasekar, H., Schwartz, R. E., Christine, K. S., Rice, C. M., van Oudenaarden, A., and Bhatia, S. N.
Virology, vol. 494, pp. 236 - 247 (2016)

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